The gene expression profile in the synovium as a predictor of the clinical response to infliximab treatment in rheumatoid arthritis.

BACKGROUND: Although the use of TNF inhibitors has fundamentally changed the way rheumatoid arthritis (RA) is treated, not all patients respond well. It is desirable to facilitate the identification of responding and non-responding patients prior to treatment, not only to avoid unnecessary treatment...

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Main Authors: Johan Lindberg, Carla A Wijbrandts, Lisa G van Baarsen, Gustavo Nader, Lars Klareskog, Anca Catrina, Rogier Thurlings, Margriet Vervoordeldonk, Joakim Lundeberg, Paul P Tak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2892481?pdf=render