pARIS-htt: an optimised expression platform to study huntingtin reveals functional domains required for vesicular trafficking
<p>Abstract</p> <p>Background</p> <p>Huntingtin (htt) is a multi-domain protein of 350 kDa that is mutated in Huntington's disease (HD) but whose function is yet to be fully understood. This absence of information is due in part to the difficulty of manipulating la...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-06-01
|
| Series: | Molecular Brain |
| Online Access: | http://www.molecularbrain.com/content/3/1/17 |