A Quantitative HILIC–MS/MS Assay of the Metabolic Response of Huh-7 Cells Exposed to 2,3,7,8-Tetrachlorodibenzo-<i>p</i>-Dioxin

A Quantitative HILIC–MS/MS Assay of the Metabolic Response of Huh-7 Cells Exposed to 2,3,7,8-Tetrachlorodibenzo-<i>p</i>-Dioxin

A hydrophilic interaction liquid chromatography (HILIC)&#8722;ultra high-pressure liquid chromatography (UHPLC) coupled with tandem mass spectrometry (MS/MS) method was developed and applied to profile metabolite changes in human Huh-7 cells exposed to the potent aryl hydrocarbon receptor (AHR)...

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Bibliographic Details
Main Authors: Qing Liu, Jingwei Cai, Robert G. Nichols, Yuan Tian, Jintao Zhang, Philip B. Smith, Yan Wang, Chao Yan, Andrew D. Patterson
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Metabolites
Subjects:
polar metabolites
HILIC–UHPLC–MS/MS
targeted metabolomics
TCDD
Online Access:https://www.mdpi.com/2218-1989/9/6/118

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https://www.mdpi.com/2218-1989/9/6/118

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