Discoidin domain receptor 1 contributes to tumorigenesis through modulation of TGFBI expression.

Discoidin domain receptor 1 (DDR1) is a member of the receptor tyrosine kinase family. The receptor is activated upon binding to its ligand, collagen, and plays a crucial role in many fundamental processes such as cell differentiation, adhesion, migration and invasion. Although DDR1 is expressed in...

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Bibliographic Details
Main Authors: Nandini Rudra-Ganguly, Christine Lowe, Michael Mattie, Mi Sook Chang, Daulet Satpayev, Alla Verlinsky, Zili An, Liping Hu, Peng Yang, Pia Challita-Eid, David R Stover, Daniel S Pereira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4219757?pdf=render