Systemic inflammation in progressive multiple sclerosis involves follicular T-helper, Th17- and activated B-cells and correlates with progression.

Systemic inflammation in progressive multiple sclerosis involves follicular T-helper, Th17- and activated B-cells and correlates with progression.

Pathology studies of progressive multiple sclerosis (MS) indicate a major role of inflammation including Th17-cells and meningeal inflammation with ectopic lymphoid follicles, B-cells and plasma cells, the latter indicating a possible role of the newly identified subset of follicular T-helper (TFH)...

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Bibliographic Details
Main Authors: Jeppe Romme Christensen, Lars Börnsen, Rikke Ratzer, Fredrik Piehl, Mohsen Khademi, Tomas Olsson, Per Soelberg Sørensen, Finn Sellebjerg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3585852?pdf=render

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http://europepmc.org/articles/PMC3585852?pdf=render

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