Hepatoportal Leptin Sensors and Their Reflex Effects on Autonomic Outflow in the Rat
Afferent nerve signals were recorded from a peripheral cut end of the small nerve bundle of the hepatic branch of the vagus nerve in anesthetized rats. An injection of leptin (100 pg, 0.1 mL) into the portal vein facilitated the afferent activity. The response was dose dependent. Further, an intrave...
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| Format: | Article |
| Language: | English |
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Hindawi Limited
2011-01-01
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| Series: | Journal of Obesity |
| Online Access: | http://dx.doi.org/10.1155/2011/516842 |