The insight of in vitro and in silico studies on cholinesterase inhibitors from the roots of Cimicifuga dahurica (Turcz.) Maxim.

The insight of in vitro and in silico studies on cholinesterase inhibitors from the roots of Cimicifuga dahurica (Turcz.) Maxim.

Cholinesterases (ChEs) are enzymes that break down neurotransmitters associated with cognitive function and memory. We isolated cinnamic acids (1 and 2), indolinones (3 and 4), and cycloartane triterpenoid derivatives (5–19) from the roots of Cimicifuga dahurica (Turcz.) Maxim. by chromatography. Th...

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Bibliographic Details
Main Authors: Jang Hoon Kim, Nguyen Phuong Thao, Yoo Kyong Han, Young Suk Lee, Bui Thi Thuy Luyen, Ha Van Oanh, Young Ho Kim, Seo Young Yang
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
Cimicifuga dahurica
Ranunculaceae
cholinestereases inhibitor
molecular simulation
Online Access:http://dx.doi.org/10.1080/14756366.2018.1491847

Internet

http://dx.doi.org/10.1080/14756366.2018.1491847

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