iNOS activity is necessary for the cytotoxic and immunogenic effects of doxorubicin in human colon cancer cells

<p>Abstract</p> <p>Background</p> <p>Doxorubicin is one of the few chemotherapeutic drugs able to exert both cytotoxic and pro-immunogenic effects against cancer cells. Following the drug administration, the intracellular protein calreticulin is translocated with an unk...

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Bibliographic Details
Main Authors: Ghigo Dario, Matera Lina, Gazzano Elena, Brusa Davide, Kopecka Joanna, De Boo Sara, Bosia Amalia, Riganti Chiara
Format: Article
Language:English
Published: BMC 2009-11-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/8/1/108