ADRB2 Arg16Gly Polymorphism and Pulmonary Function Response of Inhaled Corticosteroids plus Long-Acting Beta Agonists for Asthma Treatment: A Systematic Review and Meta-Analysis

Background. The beta-2 adrenergic receptor (ADRB2) Arg16Gly polymorphism may alter the bronchodilation response to long-acting beta2-agonists, thereby influencing the clinical effectiveness of LABAs plus corticosteroids (ICS) treatment. But the results of individual studies are inconclusive. Methods...

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Bibliographic Details
Main Authors: Xi Wang, Qian Li, Ruming Liu, Jin He, Di Wu, Yun Wang, Jun Zhang
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2018/5712805