Regulation of Dual-Specificity Phosphatase (DUSP) Ubiquitination and Protein Stability

Mitogen-activated protein kinases (MAPKs) are key regulators of signal transduction and cell responses. Abnormalities in MAPKs are associated with multiple diseases. Dual-specificity phosphatases (DUSPs) dephosphorylate many key signaling molecules, including MAPKs, leading to the regulation of dura...

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Bibliographic Details
Main Authors: Hsueh-Fen Chen, Huai-Chia Chuang, Tse-Hua Tan
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/20/11/2668