Mild and Efficient Winterfeldt Oxidation of 1,2,3,4-Tetrahydro-γ-carbolines for the Synthesis of Dihydropyrrolo[3,2-b]-quinolones and Pyrrolo[3,2-b]quinolones

Mild and Efficient Winterfeldt Oxidation of 1,2,3,4-Tetrahydro-γ-carbolines for the Synthesis of Dihydropyrrolo[3,2-b]-quinolones and Pyrrolo[3,2-b]quinolones

The Winterfeldt oxidation (NaOH, DMF, air, rt) of substituted 1,2,3,4-tetrahydro-γ-carbolines has been developed, which provides a convenient and efficient method for the synthesis of the corresponding dihydropyrrolo[3,2-b]quinolones in moderate to excellent yields (38–94%). The generality and subst...

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Bibliographic Details
Main Authors: Rong Sheng, Jiangwei Zhu, Yongzhou Hu
Format: Article
Language:English
Published: MDPI AG 2012-01-01
Series:Molecules
Subjects:
: Winterfeldt oxidation
1,2,3,4-tetrahydro-γ-carbolines
dihydropyrrolo[3,2-b]-quinolones
pyrrolo[3,2-b]quinolones
Online Access:http://www.mdpi.com/1420-3049/17/2/1177/

Internet

http://www.mdpi.com/1420-3049/17/2/1177/

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