Quality and freshness of human bone marrow-derived mesenchymal stem cells decrease over time after trypsinization and storage in phosphate-buffered saline

Abstract Human bone marrow-derived mesenchymal stem cells (hBM-MSCs) have been studied for their therapeutic potential. However, evaluating the quality of hBM-MSCs before transplantation remains a challenge. We addressed this issue in the present study by investigating deformation, the expression of...

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Bibliographic Details
Main Authors: Tae Hwan Shin, Seungah Lee, Ki Ryung Choi, Da Yeon Lee, Yongman Kim, Man Jeong Paik, Chan Seo, Seok Kang, Moon Suk Jin, Tae Hyeon Yoo, Seong Ho Kang, Gwang Lee
Format: Article
Language:English
Published: Nature Publishing Group 2017-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01315-0