A computational approach to understand in vitro alveolar morphogenesis.

Primary human alveolar type II (AT II) epithelial cells maintained in Matrigel cultures form alveolar-like cysts (ALCs) using a cytogenesis mechanism that is different from that of other studied epithelial cell types: neither proliferation nor death is involved. During ALC formation, AT II cells eng...

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Bibliographic Details
Main Authors: Sean H J Kim, Wei Yu, Keith Mostov, Michael A Matthay, C Anthony Hunt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2653231?pdf=render