Lipopolysaccharide-induced neuroinflammation leads to the accumulation of ubiquitinated proteins and increases susceptibility to neurodegeneration induced by proteasome inhibition in rat hippocampus

Lipopolysaccharide-induced neuroinflammation leads to the accumulation of ubiquitinated proteins and increases susceptibility to neurodegeneration induced by proteasome inhibition in rat hippocampus

<p><b>Abstract</b></p> <p><b>Background</b></p> <p>Neuroinflammation and protein accumulation are characteristic hallmarks of both normal aging and age-related neurodegenerative diseases. However, the relationship between these factors in neurode...

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Bibliographic Details
Main Authors: Pintado Cristina, Gavilán María P, Gavilán Elena, García-Cuervo Luisa, Gutiérrez Antonia, Vitorica Javier, Castaño Angélica, Ríos Rosa M, Ruano Diego
Format: Article
Language:English
Published: BMC 2012-05-01
Series:Journal of Neuroinflammation
Subjects:
Immunoproteasome
Neurodegeneration
Neurodegenerative diseases
Neuroinflammation
Protein accumulation
Online Access:http://www.jneuroinflammation.com/content/9/1/87

Internet

http://www.jneuroinflammation.com/content/9/1/87

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