Stepwise design, synthesis, and in vitro antifungal screening of (Z)-substituted-propenoic acid derivatives with potent broad-spectrum antifungal activity

Mohammed A KhedrDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Helwan University, Cairo, EgyptAbstract: Fungal infections are a main reason for the high mortality rate worldwide. It is a challenge to design selective antifungal agents with broad-spectrum activity. Lanosterol 14&alp...

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Bibliographic Details
Main Author: Khedr MA
Format: Article
Language:English
Published: Dove Medical Press 2015-08-01
Series:Drug Design, Development and Therapy
Online Access:http://www.dovepress.com/stepwise-design-synthesis-and-in-vitro-antifungal-screening-of-z-subst-peer-reviewed-article-DDDT