AXL phosphorylates and up-regulates TNS2 and its implications in IRS-1-associated metabolism in cancer cells

AXL phosphorylates and up-regulates TNS2 and its implications in IRS-1-associated metabolism in cancer cells

Abstract Background TNS2 is a focal adhesions protein and a binding partner for many proteins, including the receptor tyrosine kinase Axl. Although TNS2 can bind with Axl, the details of their interactions have not been elucidated. TNS2 is involved in IRS-1 signaling pathway. In this study, we confi...

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Bibliographic Details
Main Authors: Li-Chun Cheng, Yen-Lin Chen, An-Ning Cheng, Alan Yueh-Luen Lee, Chun-Yu Cho, Jhy-Shrian Huang, Shuang-En Chuang
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Journal of Biomedical Science
Subjects:
Axl
Tensin2
C1-TEN
IRS1
PDK1
Glut4
Online Access:http://link.springer.com/article/10.1186/s12929-018-0465-x

Internet

http://link.springer.com/article/10.1186/s12929-018-0465-x

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