The PAX1 locus at 20p11 is a potential genetic modifier for bilateral cleft lip

The PAX1 locus at 20p11 is a potential genetic modifier for bilateral cleft lip

Summary: Nonsyndromic orofacial clefts (OFCs) are a common birth defect and are phenotypically heterogenous in the structure affected by the cleft—cleft lip (CL) and cleft lip and palate (CLP)—as well as other features, such as the severity of the cleft. Here, we focus on bilateral and unilateral cl...

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Bibliographic Details
Main Authors: Sarah W. Curtis, Daniel Chang, Myoung Keun Lee, John R. Shaffer, Karlijne Indencleef, Michael P. Epstein, David J. Cutler, Jeffrey C. Murray, Eleanor Feingold, Terri H. Beaty, Peter Claes, Seth M. Weinberg, Mary L. Marazita, Jenna C. Carlson, Elizabeth J. Leslie
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:HGG Advances
Subjects:
GWAS
orofacial cleft
modifier
facial variation
upper lip
laterality
Online Access:http://www.sciencedirect.com/science/article/pii/S2666247721000063

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http://www.sciencedirect.com/science/article/pii/S2666247721000063

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