CaSR Induces Osteoclast Differentiation and Promotes Bone Metastasis in Lung Adenocarcinoma

CaSR Induces Osteoclast Differentiation and Promotes Bone Metastasis in Lung Adenocarcinoma

Objective: Explore the mechanism of CaSR's involvement in bone metastasis in lung adenocarcinoma.Methods: Immunohistochemistry (IHC) was used to detect the expression of calcium-sensing receptor (CaSR) in 120 cases of lung adenocarcinoma with bone metastasis. Stably transfected cell lines with...

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Bibliographic Details
Main Authors: Lian Liu, Yichang Fan, Zhaoxin Chen, Yujian Zhang, Jing Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Oncology
Subjects:
calcium-sensing receptor
proliferation
migration
bone metastasis
lung adenocarcinoma
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00305/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.00305/full

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