Increased Expression of Fibulin-1 Is Associated With Hepatocellular Carcinoma Progression by Regulating the Notch Signaling Pathway

Increased Expression of Fibulin-1 Is Associated With Hepatocellular Carcinoma Progression by Regulating the Notch Signaling Pathway

Fibulin-1, a component of the extracellular matrix (ECM), its prognostic, pathophysiologic and diagnostic role in hepatocellular carcinoma (HCC) is still unexplored. We first found that either Fibulin-1 messenger RNA (mRNA) or protein level was highly elevated in HCC tissues compared with normal tis...

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Bibliographic Details
Main Authors: Jiao Gong, Yusheng Jie, Cuicui Xiao, Wenying Zhou, Xinhua Li, Yaqiong Chen, Yuankai Wu, Jing Cao, Qi Zhang, Zhiliang Gao, Bo Hu, Yutian Chong
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Fibulin-1
hepatocellular carcinoma
apoptosis
serum marker
circulating RNA
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00478/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00478/full

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