A role for the Sts phosphatases in negatively regulating IFNγ‐mediated production of nitric oxide in monocytes

Abstract Introduction The atypical Sts phosphatases negatively regulate signaling pathways in diverse immune cell types, with two of their molecular targets being the related kinases Syk and Zap‐70. Mice lacking Sts expression (Sts−/−) are resistant to infection by the live vaccine strain (LVS) of F...

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Bibliographic Details
Main Authors: Kaustubh Parashar, Nicholas Carpino
Format: Article
Language:English
Published: Wiley 2020-12-01
Series:Immunity, Inflammation and Disease
Subjects:
Syk
Online Access:https://doi.org/10.1002/iid3.336