Zinc supplementation improves heme biosynthesis in rats exposed to lead

BACKGROUND Lead acetate (Pb) inhibits heme biosynthesis through inhibition of δ-aminolevulinic acid dehydrogenase (δ-ALAD), copro porphyrinogen oxidase, and ferro chelatase. Zinc supplementation increases lead-binding metallothionein proteins. The purpose of this study was to find evidence that zinc...

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Bibliographic Details
Main Authors: Budi Santoso, Hertanto Wahyu Subagio, Lisyani Suromo, Henna Rya Sunomo
Format: Article
Language:English
Published: Faculty of Medicine Trisakti University 2016-02-01
Series:Universa Medicina
Subjects:
Online Access:https://univmed.org/ejurnal/index.php/medicina/article/view/10