Heparan Sulfate Proteoglycans: Key Mediators of Stem Cell Function

Heparan sulfate proteoglycans (HSPGs) are an evolutionarily ancient subclass of glycoproteins with exquisite structural complexity. They are ubiquitously expressed across tissues and have been found to exert a multitude of effects on cell behavior and the surrounding microenvironment. Evidence has s...

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Bibliographic Details
Main Authors: Maanasa Ravikumar, Raymond Alexander Alfred Smith, Victor Nurcombe, Simon M. Cool
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.581213/full