Total Flavonoids of Rhizoma Drynariae Promotes Differentiation of Osteoblasts and Growth of Bone Graft in Induced Membrane Partly by Activating Wnt/β-Catenin Signaling Pathway

Total Flavonoids of Rhizoma Drynariae Promotes Differentiation of Osteoblasts and Growth of Bone Graft in Induced Membrane Partly by Activating Wnt/β-Catenin Signaling Pathway

Total flavonoids of Rhizoma drynariae (TFRD), a Chinese medicine, is widely used in the treatment of fracture, bone defect, osteoporosis and other orthopedic diseases, and has achieved good effects. Purpose of this trial was to explore efficacy of TFRD on bone graft’s mineralization and osteoblasts’...

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Bibliographic Details
Main Authors: Shuyuan Li, Hongliang Zhou, Cheng Hu, Jiabao Yang, Jinfei Ye, Yuexi Zhou, Zige Li, Leilei Chen, Qishi Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
total flavonoids of rhizoma drynariae
induced membrane
Wnt/β-catenin
bone defect
osteogenic efficacy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.675470/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.675470/full

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