Tissue-protective effects of NKG2A in immune-mediated clearance of virus infection.

Virus infection triggers a CD8(+) T cell response that aids in virus clearance, but also expresses effector functions that may result in tissue injury. CD8(+) T cells express a variety of activating and inhibiting ligands, though regulation of the expression of inhibitory receptors is not well under...

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Bibliographic Details
Main Authors: Kenneth H Ely, Mitsuo Matsuoka, Matthew P DeBerge, Jessica A Ruby, Jun Liu, Mark J Schneider, Yan Wang, Young S Hahn, Richard I Enelow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4177548?pdf=render