Synthesis and characterization of a new bile acid and platinum(II) complex with cytostatic activity

With a view to using bile acids as shuttles for delivering platinum-related cytostatic drugs to the liver, a cholylglycine(CG)-derivative of platinum(II) has been synthesized. The complex, named Bamet-H2, was characterized by elemental analysis, FT-IR, NMR, FAB-MS, and UV spectroscopy. The results i...

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Bibliographic Details
Main Authors: J J Criado, M C Herrera, M F Palomero, M Medarde, E Rodriguez, J J Marin
Format: Article
Language:English
Published: Elsevier 1997-05-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520372266