In silico repurposing of antipsychotic drugs for Alzheimer’s disease

In silico repurposing of antipsychotic drugs for Alzheimer’s disease

Abstract Background Alzheimer’s disease (AD) is the most prevalent form of dementia and represents one of the highest unmet requirements in medicine today. There is shortage of novel molecules entering into market because of poor pharmacokinetic properties and safety issues. Drug repurposing offers...

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Bibliographic Details
Main Authors: Shivani Kumar, Suman Chowdhury, Suresh Kumar
Format: Article
Language:English
Published: BMC 2017-10-01
Series:BMC Neuroscience
Subjects:
Drug repurposing
Alzheimer’s disease
Antipsychotic drugs
Acetylcholinesterase
Butyrylcholinesterase
Beta-secretase cleavage enzyme
Online Access:http://link.springer.com/article/10.1186/s12868-017-0394-8

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http://link.springer.com/article/10.1186/s12868-017-0394-8

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