Quantifying the protection of activating and inhibiting NK cell receptors during infection with a CMV-like virus

The responsiveness of natural killer (NK) cells is controlled by balancing signals from activating and inhibitory receptors. <br/>The most important ligands of inhibitory NK cell receptors are the highly polymorphic major histocompatibility complex (MHC) class I molecules, which allow NK cells...

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Bibliographic Details
Main Authors: Rob J De Boer, Can eKesmir, Paola eCarrillo-Bustamante
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00020/full