Spatio-selective activation of nuclear translocation of YAP with light directs invasion of cancer cell spheroids

Spatio-selective activation of nuclear translocation of YAP with light directs invasion of cancer cell spheroids

Summary: The mechanical properties of the extracellular matrix strongly influence tumor progression and invasion. Yes-associated protein (YAP) has been shown to be a key regulator of this process translating mechanical cues from the extracellular matrix into intracellular signals. Despite its appare...

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Bibliographic Details
Main Authors: Bernhard Illes, Adrian Fuchs, Florian Gegenfurtner, Evelyn Ploetz, Stefan Zahler, Angelika M. Vollmar, Hanna Engelke
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:iScience
Subjects:
Molecular Biology
Cell Biology
Biological Sciences Tools
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422100153X

Internet

http://www.sciencedirect.com/science/article/pii/S258900422100153X

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