NSOM/QD-based direct visualization of CD3-induced and CD28-enhanced nanospatial coclustering of TCR and coreceptor in nanodomains in T cell activation.

NSOM/QD-based direct visualization of CD3-induced and CD28-enhanced nanospatial coclustering of TCR and coreceptor in nanodomains in T cell activation.

Direct molecular imaging of nano-spatial relationship between T cell receptor (TCR)/CD3 and CD4 or CD8 co-receptor before and after activation of a primary T cell has not been reported. We have recently innovated application of near-field scanning optical microscopy (NSOM) and immune-labeling quantu...

Full description

Bibliographic Details
Main Authors: Liyun Zhong, Gucheng Zeng, Xiaoxu Lu, Richard C Wang, Guangming Gong, Lin Yan, Dan Huang, Zheng W Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2693923?pdf=render

Internet

http://europepmc.org/articles/PMC2693923?pdf=render

Similar Items