Ranking metrics in gene set enrichment analysis: do they matter?

Abstract Background There exist many methods for describing the complex relation between changes of gene expression in molecular pathways or gene ontologies under different experimental conditions. Among them, Gene Set Enrichment Analysis seems to be one of the most commonly used (over 10,000 citati...

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Bibliographic Details
Main Authors: Joanna Zyla, Michal Marczyk, January Weiner, Joanna Polanska
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-017-1674-0