Pre-treatment tumor-infiltrating T cells influence response to neoadjuvant chemoradiotherapy in esophageal adenocarcinoma

Pre-treatment tumor-infiltrating T cells influence response to neoadjuvant chemoradiotherapy in esophageal adenocarcinoma

Esophageal adenocarcinoma (EAC) is a disease with dismal treatment outcomes. Response to neoadjuvant chemoradiation (CRT) varies greatly. Although the underlying mechanisms of CRT resistance are not identified, accumulating evidence indicates an important role for local antitumor immunity. To explor...

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Bibliographic Details
Main Authors: R.S.A. Goedegebuure, M. Harrasser, L.K. de Klerk, T.S. van Schooten, N.C.T. van Grieken, M. Eken, M.S. Grifhorst, N. Pocorni, E.S. Jordanova, M.I. van Berge Henegouwen, R.E. Pouw, H.M.W. Verheul, J.J. van der Vliet, H.W.M. van Laarhoven, V.L.J.L Thijssen, A.J. Bass, T.D. De Gruijl, S. Derks
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:OncoImmunology
Subjects:
tumor microenvironment
esophageal cancer
chemoradiation
immune response
liquid biopsy
Online Access:http://dx.doi.org/10.1080/2162402X.2021.1954807

Internet

http://dx.doi.org/10.1080/2162402X.2021.1954807

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