Discrepancy of p16 immunohistochemical expression and HPV RNA in penile cancer. A multiplex in situ hybridization/immunohistochemistry approach study

Discrepancy of p16 immunohistochemical expression and HPV RNA in penile cancer. A multiplex in situ hybridization/immunohistochemistry approach study

Abstract Background The high-risk human papillomavirus (HPV) infection represents one of the main etiologic pathways of penile carcinogenesis in approximately 30–50 % of cases. Several techniques for the detection of HPV are currently available including Polymerase chain reaction-based techniques, D...

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Bibliographic Details
Main Authors: Federico Zito Marino, Rosalaura Sabetta, Francesca Pagliuca, Matteo Brunelli, Gabriella Aquino, Sisto Perdonà, Gerardo Botti, Gaetano Facchini, Francesco Fiorentino, Giovanni Di Lauro, Marco De Sio, Ferdinando De Vita, Giorgio Toni, Rodolfo Borges Dos Reis, Luciano Neder, Renato Franco
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Infectious Agents and Cancer
Subjects:
ISH
HPV
p16
Penile carcinoma
Multiplex HPV RNA ISH /p16 IHC
Online Access:https://doi.org/10.1186/s13027-021-00361-8

Internet

https://doi.org/10.1186/s13027-021-00361-8

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