Piecing Together How Peroxiredoxins Maintain Genomic Stability

Piecing Together How Peroxiredoxins Maintain Genomic Stability

Peroxiredoxins, a highly conserved family of thiol oxidoreductases, play a key role in oxidant detoxification by partnering with the thioredoxin system to protect against oxidative stress. In addition to their peroxidase activity, certain types of peroxiredoxins possess other biochemical activities,...

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Bibliographic Details
Main Authors: James D. West, Trevor J. Roston, Joseph B. David, Kristin M. Allan, Matthew A. Loberg
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Antioxidants
Subjects:
peroxiredoxin
oxidative stress
thioredoxin
thiol peroxidase
mutator
genomic instability
sulfiredoxin
redox switch
ribonucleotide reductase
Online Access:https://www.mdpi.com/2076-3921/7/12/177

Internet

https://www.mdpi.com/2076-3921/7/12/177

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