SHH-N non-canonically sustains androgen receptor activity in androgen-independent prostate cancer cells

Abstract Prostate cancer is the second most frequent cancer diagnosed in men worldwide. Localized disease can be successfully treated, but advanced cases are more problematic. After initial effectiveness of androgen deprivation therapy, resistance quickly occurs. Therefore, we aimed to investigate t...

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Bibliographic Details
Main Authors: Diana Trnski, Maja Sabol, Sanja Tomić, Ivan Štefanac, Milanka Mrčela, Vesna Musani, Nikolina Rinčić, Matea Kurtović, Tina Petrić, Sonja Levanat, Petar Ozretić
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-93971-6