Enhancing adoptive CD8 T cell therapy by systemic delivery of tumor associated antigens

Enhancing adoptive CD8 T cell therapy by systemic delivery of tumor associated antigens

Abstract Adoptive T-cell transfer (ACT) offers a curative therapeutic option for subsets of melanoma and hematological cancer patients. To increase response rates and broaden the applicability of ACT, it is necessary to improve the post-infusion performance of the transferred T cells. The design of...

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Bibliographic Details
Main Authors: Ditte E. Jæhger, Mie L. Hübbe, Martin K. Kræmer, Gael Clergeaud, André V. Olsen, Camilla Stavnsbjerg, Mette N. Wiinholt, Andreas Kjær, Jonas R. Henriksen, Anders E. Hansen, Thomas L. Andresen
Format: Article
Language:English
Published: Nature Publishing Group 2021-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-99347-0

Internet

https://doi.org/10.1038/s41598-021-99347-0

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