Vascular remodeling is governed by a VEGFR3-dependent fluid shear stress set point

Vascular remodeling is governed by a VEGFR3-dependent fluid shear stress set point

Vascular remodeling under conditions of growth or exercise, or during recovery from arterial restriction or blockage is essential for health, but mechanisms are poorly understood. It has been proposed that endothelial cells have a preferred level of fluid shear stress, or ‘set point’, that determine...

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Bibliographic Details
Main Authors: Nicolas Baeyens, Stefania Nicoli, Brian G Coon, Tyler D Ross, Koen Van den Dries, Jinah Han, Holly M Lauridsen, Cecile O Mejean, Anne Eichmann, Jean-Leon Thomas, Jay D Humphrey, Martin A Schwartz
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-02-01
Series:eLife
Subjects:
mechanotransduction
shear stress
vascular remodeling
arteriogenesis
homeostasis
Online Access:https://elifesciences.org/articles/04645

Internet

https://elifesciences.org/articles/04645

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