KRAS, NRAS, BRAF, HER2 and microsatellite instability in metastatic colorectal cancer – practical implications for the clinician

KRAS, NRAS, BRAF, HER2 and microsatellite instability in metastatic colorectal cancer – practical implications for the clinician

Colorectal cancer is a successful model of genetic biomarker development in oncology. Currently, several predictive or prognostic genetic alterations have been identified and are used in clinical practice. The RAS gene family, which includes KRAS and NRAS act as predictors for anti-epithelial growth...

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Bibliographic Details
Main Authors: Afrăsânie Vlad-Adrian, Marinca Mihai Vasile, Alexa-Stratulat Teodora, Gafton Bogdan, Păduraru Marius, Adavidoaiei Anca Maria, Miron Lucian, Rusu Cristina
Format: Article
Language:English
Published: Sciendo 2019-09-01
Series:Radiology and Oncology
Subjects:
metastatic colorectal cancer
kras
nras
braf
her2
microsatellite instability
Online Access:https://doi.org/10.2478/raon-2019-0033

Internet

https://doi.org/10.2478/raon-2019-0033

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