Development of a Novel Orthotopic Gastric Cancer Mouse Model

Development of a Novel Orthotopic Gastric Cancer Mouse Model

Abstract Background Gastric cancer metastasis is a highly fatal disease with a five-year survival rate of less than 5%. One major obstacle in studying gastric cancer metastasis is the lack of faithful models available. The cancer xenograft mouse models are widely used to elucidate the mechanisms of...

Full description

Bibliographic Details
Main Authors: Wonyoung Kang, Leigh Maher, Michael Michaud, Seong-Woo Bae, Seongyeong Kim, Hye Seung Lee, Seock-Ah Im, Han-Kwang Yang, Charles Lee
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Biological Procedures Online
Subjects:
Gastric cancer
Metastasis
Orthotopic xenograft
Patient-derived xenograft (PDX)
Tumor mouse model
Online Access:https://doi.org/10.1186/s12575-020-00137-1

Internet

https://doi.org/10.1186/s12575-020-00137-1

Similar Items