Tissue-Specific Expression of the Low-Affinity IgG Receptor, FcγRIIb, on Human Mast Cells

Tissue-Specific Expression of the Low-Affinity IgG Receptor, FcγRIIb, on Human Mast Cells

Immediate hypersensitivity reactions are induced by the interaction of allergens with specific IgE antibodies bound via FcεRI to mast cells and basophils. While these specific IgE antibodies are needed to trigger such reactions, not all individuals harboring IgE exhibit symptoms of allergy. The lack...

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Bibliographic Details
Main Authors: Oliver T. Burton, Alexandra Epp, Manoussa E. Fanny, Samuel J. Miller, Amanda J. Stranks, Jessica E. Teague, Rachael A. Clark, Matt van de Rijn, Hans C. Oettgen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
IgE
IgG
FcγRIIb
Fc receptors
mast cells
anaphylaxis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01244/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01244/full

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