Deformation of Mitochondrial Cristae in Human Neural Progenitor Cells Exposed to Valproic Acid

Deformation of Mitochondrial Cristae in Human Neural Progenitor Cells Exposed to Valproic Acid

ABSTRACT Neural development represents a dynamic process where mitochondrial integrity is decisive for neuronal activity. Structural changes in these organelles may be related to neurological disorders. Valproic acid (VPA) is an anticonvulsive drug commonly used for epilepsy treatment and its use is...

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Bibliographic Details
Main Authors: RODRIGO M. DA COSTA, KARINA KARMIRIAN, STEVENS K. REHEN
Format: Article
Language:English
Published: Academia Brasileira de Ciências 2018-04-01
Series:Anais da Academia Brasileira de Ciências
Subjects:
transmission electron microscopy
mitochondria
valproic acid
epilepsy
human neural progenitor cells
electron tomography
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018005007106&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018005007106&lng=en&tlng=en

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