Obesity‐induced MBD2_v2 expression promotes tumor‐initiating triple‐negative breast cancer stem cells

Obesity‐induced MBD2_v2 expression promotes tumor‐initiating triple‐negative breast cancer stem cells

Obesity is a risk factor for triple‐negative breast cancer (TNBC) incidence and poor outcomes, but the underlying molecular biology remains unknown. We previously identified in TNBC cell cultures that expression of epigenetic reader methyl‐CpG‐binding domain protein 2 (MBD2), specifically the altern...

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Bibliographic Details
Main Authors: Emily A. Teslow, Cristina Mitrea, Bin Bao, Ramzi M. Mohammad, Lisa A. Polin, Greg Dyson, Kristen S. Purrington, Aliccia Bollig‐Fischer
Format: Article
Language:English
Published: Wiley 2019-04-01
Series:Molecular Oncology
Subjects:
cancer stem cell‐like cells
MBD2
MBD2_v2
obesity
SRSF2
triple‐negative breast cancer
Online Access:https://doi.org/10.1002/1878-0261.12444

Internet

https://doi.org/10.1002/1878-0261.12444

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