Pleiotropic effects of Sox2 during the development of the zebrafish epithalamus.

The zebrafish epithalamus is part of the diencephalon and encompasses three major components: the pineal, the parapineal and the habenular nuclei. Using sox2 knockdown, we show here that this key transcriptional regulator has pleiotropic effects during the development of these structures. Sox2 negat...

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Bibliographic Details
Main Authors: Sofia Pavlou, Katy Astell, Ioannis Kasioulis, Milica Gakovic, Richard Baldock, Veronica van Heyningen, Pedro Coutinho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3909122?pdf=render