The Eukaryotic Elongation Factor 1 Alpha (eEF1α) from the Parasite Leishmania infantum Is Modified with the Immunomodulatory Substituent Phosphorylcholine (PC)

The Eukaryotic Elongation Factor 1 Alpha (eEF1α) from the Parasite Leishmania infantum Is Modified with the Immunomodulatory Substituent Phosphorylcholine (PC)

Proteins and glycolipids have been found to be decorated with phosphorylcholine (PC) both in protozoa and nematodes that parasitize humans and animals. PC epitopes can provoke various effects on immune cells leading to an immunomodulation of the host’s immune system that allows long-term persistence...

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Bibliographic Details
Main Authors: Thomas Timm, Giada Annoscia, Jochen Klein, Günter Lochnit
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Molecules
Subjects:
Leishmania infantum
promastigote
proteomics
phosphorylcholine
immunomodulation
immunofluorescence
Online Access:https://www.mdpi.com/1420-3049/22/12/2094

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