Peiminine Protects against Lipopolysaccharide-Induced Mastitis by Inhibiting the AKT/NF-κB, ERK1/2 and p38 Signaling Pathways

Peiminine Protects against Lipopolysaccharide-Induced Mastitis by Inhibiting the AKT/NF-κB, ERK1/2 and p38 Signaling Pathways

Peiminine, an alkaloid extracted from Fritillaria plants, has been reported to have potent anti-inflammatory properties. However, the anti-inflammatory effect of peiminine on a mouse lipopolysaccharide (LPS)-induced mastitis model remains to be elucidated. The purpose of this experiment was to inves...

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Bibliographic Details
Main Authors: Qian Gong, Yanwei Li, He Ma, Wenjin Guo, Xingchi Kan, Dianwen Xu, Juxiong Liu, Shoupeng Fu
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:International Journal of Molecular Sciences
Subjects:
peiminine
mastitis
LPS
AKT/NF-κB
ERK1/2
p38
Online Access:http://www.mdpi.com/1422-0067/19/9/2637

Internet

http://www.mdpi.com/1422-0067/19/9/2637

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