The Emerging Role of Lamin C as an Important LMNA Isoform in Mechanophenotype

Lamin A and lamin C isoforms of the gene LMNA are major structural and mechanotransductive components of the nuclear lamina. Previous reports have proposed lamin A as the isoform with the most dominant contributions to cellular mechanophenotype. Recently, expression of lamin C has also been shown to...

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Bibliographic Details
Main Authors: Rafael D. González-Cruz, Kris N. Dahl, Eric M. Darling
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2018.00151/full