Stability and Safety Traits of Novel Cyclosporine A and Tacrolimus Ophthalmic Galenic Formulations Involved in Vernal Keratoconjunctivitis Treatment by a High-Resolution Mass Spectrometry Approach

Stability and Safety Traits of Novel Cyclosporine A and Tacrolimus Ophthalmic Galenic Formulations Involved in Vernal Keratoconjunctivitis Treatment by a High-Resolution Mass Spectrometry Approach

In this study, a sensitive quantitative method based on high performance liquid chromatography combined with high-resolution mass spectrometry, Q Exactive<sup>TM</sup>-Orbitrap<sup>®</sup> was set up and applied for the determination of the immunosuppressor agents cyclosporin...

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Bibliographic Details
Main Authors: Daniele Giovanni Ghiglioni, Piera Anna Martino, Gaia Bruschi, Davide Vitali, Silvia Osnaghi, Maria Grazia Corti, Giangiacomo Beretta
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Pharmaceutics
Subjects:
cyclosporine A
tacrolimus
ophthalmic formulations
vernal keratoconjunctivitis
Online Access:https://www.mdpi.com/1999-4923/12/4/378

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https://www.mdpi.com/1999-4923/12/4/378

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