Newly identified roles of PML in stem cell biology

It has long been believed that the tumor suppressor promyelocytic leukemia (PML), the core component of the nuclear substructures known as the PML-nuclear bodies, plays a key part in acute promyelocytic leukemia (APL), as it is first cloned at the breakpoint of the t(15;17) translocation typical of...

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Bibliographic Details
Main Authors: Keisuke eIto, Kyoko eIto
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-03-01
Series:Frontiers in Oncology
Subjects:
PML
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00050/full