Perinatal n-3 fatty acid deficiency selectively reduces myo-inositol levels in the adult rat PFC: an in vivo 1H-MRS study*[S]

Perinatal n-3 fatty acid deficiency selectively reduces myo-inositol levels in the adult rat PFC: an in vivo 1H-MRS study*[S]

To investigate the effects of omega-3 fatty acid deficiency on phosphatidylinositol signaling in brain, myo-inositol (mI) concentrations were determined in the prefrontal cortex (PFC) of omega-3 fatty acid deficient rats by in vivo proton magnetic resonance spectroscopy (1H-MRS). To generate graded...

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Bibliographic Details
Main Authors: Robert K. McNamara, Jessica Able, Ronald Jandacek, Therese Rider, Patrick Tso, Diana M. Lindquist
Format: Article
Language:English
Published: Elsevier 2009-03-01
Series:Journal of Lipid Research
Subjects:
proton magnetic resonance spectroscopy
omega-3 fatty acids
docosahexaenoic acid
DHA
Myo-inositol
N-acetyl aspartate
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520308841

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http://www.sciencedirect.com/science/article/pii/S0022227520308841

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