Tethered Signaling in Inhibitory Immune Receptors

Leukocytes play critical roles in preventing pathogenic infection and controlling transformed cells, but must remain quiescent in response to healthy tissue. To execute this function, immune cells need to integrate signals from a host of activatory, co-activatory, and co-inhibitory immune receptors....

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Bibliographic Details
Main Authors: Pablo Pérez-Ferreros, Katharina Gaus, Jesse Goyette
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Physics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphy.2018.00158/full