HDAC I inhibition in the dorsal and ventral hippocampus differentially modulates predator-odor fear learning and generalization

Although predator odors are ethologically relevant stimuli for rodents, the molecular pathways and contribution of some brain regions involved remain elusive. Inhibition of histone deacetylases (HDACs) in the dorsal hippocampus has been shown to enhance shock-induced contextual fear learning, but it...

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Bibliographic Details
Main Authors: Robin K Yuan, Jenna C Hebert, Arthur S Thomas, Ellen G Wann, Isabel A Muzzio
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00319/full